Research projects of Lynn Sakai, Ph.D.
Lynn Y. Sakai, Oregon Health Sciences University Hospital

2003 - Lynn Y. Sakai, Ph.D., Associate Professor of Biochemistry and Molecular Biology, Oregon Health Sciences University and Shriners Hospital for Children, was awarded a grant for her research which has confirmed the utility of a new test to measure the concentration of fibrillin-1 protein from blood and cell cultures. This test will be used to compare the quantity of fibrillin-1 fragments in samples from mild and severe Marfan syndrome and other types of cardiovascular diseases to determine its usefulness as a future diagnostic test and its ability to monitor disease progression.

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October 2001 - The Sakai laboratory is working to understand the molecular interactions which underlie the pathogenesis of certain diseases involving fibrillin microfibrils. These diseases include the Marfan syndrome, congenital contractural arachnodactyly, and scleroderma.
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May 2000 - Structure and Function of Extracellular Matrix Molecules
Research projects of Cheryl Maslin
Cheryl Maslin, Oregon Health Sciences University Hospital

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Recipient of 1998 NMF Research Grant to study
Oregon Research
Ever since the early days of Marfan's, Oregon has been one of the primary centers of research. We are especially proud to have to our credit our very own Lynn Sakai who was on the a research team that lead to identification in 1991 of the chromosome, gene and component of connective tissue (fibrillin) in which the mutation for the Marfan syndrome is located !!  Along with Cheryl Maslin and others, research done here in Oregon continues to give hope for a better tommorow to Marfan's affected around the world.
Research projects of Cheryl Maslin
Cheryl Maslin, Oregon Health Sciences University Hospital

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Recipient of 1998 NMF Research Grant to study

This page was last updated on: June 8, 2004

Research projects of Lynn Sakai, Ph.D.
Lynn Y. Sakai, Oregon Health Sciences University Hospital

2003 - Lynn Y. Sakai, Ph.D., Associate Professor of Biochemistry and Molecular Biology, Oregon Health Sciences University and Shriners Hospital for Children, was awarded a grant for her research which has confirmed the utility of a new test to measure the concentration of fibrillin-1 protein from blood and cell cultures. This test will be used to compare the quantity of fibrillin-1 fragments in samples from mild and severe Marfan syndrome and other types of cardiovascular diseases to determine its usefulness as a future diagnostic test and its ability to monitor disease progression.

*****************************************************************************************
October 2001 - The Sakai laboratory is working to understand the molecular interactions which underlie the pathogenesis of certain diseases involving fibrillin microfibrils. These diseases include the Marfan syndrome, congenital contractural arachnodactyly, and scleroderma.
*****************************************************************************************
May 2000 - Structure and Function of Extracellular Matrix Molecules